Document Detail

Evolutionary forces on Anopheles: what makes a malaria vector?
MedLine Citation:
PMID:  20056485     Owner:  NLM     Status:  MEDLINE    
In human malaria, transmission intensity is highly dependent on the vectorial capacity and competence of local mosquitoes. Most mosquitoes are dead ends for the parasite, and only limited ranges of Anopheles are able to transmit Plasmodium to humans. Research to understand the determinants of vectorial capacity and competence has greatly progressed in recent years; however, some aspects have been overlooked and the evolutionary pressures that affect them often neglected. Here, we review key factors of vectorial capacity and competence in Anopheles, with a particular focus on the most important malaria vector Anopheles gambiae. We aim to point out selection pressures exerted by Plasmodium on Anopheles to improve its own transmission and discuss how the parasite might shape the vector to its benefit.
Anna Cohuet; Caroline Harris; Vincent Robert; Didier Fontenille
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2010-01-06
Journal Detail:
Title:  Trends in parasitology     Volume:  26     ISSN:  1471-5007     ISO Abbreviation:  Trends Parasitol.     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-02-23     Completed Date:  2010-04-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100966034     Medline TA:  Trends Parasitol     Country:  England    
Other Details:
Languages:  eng     Pagination:  130-6     Citation Subset:  IM    
Copyright Information:
Copyright 2009 Elsevier Ltd. All rights reserved.
Institut de Recherche pour le D?veloppement, UR016, Characterization and control of vector populations, Montpellier, France.
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MeSH Terms
Anopheles / parasitology,  physiology*
Bites and Stings
Insect Vectors / parasitology,  physiology*
Insecticide Resistance
Malaria / economics,  parasitology,  prevention & control,  transmission*

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