Document Detail

Evolution of retinal pigment epithelium detachment after photodynamic therapy for choroidal neovascularization in age-related macular degeneration.
MedLine Citation:
PMID:  16761259     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To report a case of pigment epithelium detachment (PED) which appeared after photodynamic therapy (PDT) and was followed up for 50 months. METHODS: Case report. RESULTS: A 71-year-old woman with occult choroidal neovascular membrane due to age-related macular degeneration (ARMD) developed PED 48 hours after PDT. The patient was studied with fluorescein angiography (FA) and optical coherence tomography (OCT). Fluorescein angiographic evidence of PED remained essentially unchanged during the follow-up period of 50 months. Although OCT initially gave clear evidence of PED, in the last 12 months of follow-up the PED appears to have resolved. CONCLUSIONS: Photodynamic treatment could be involved in the occurrence of PED in occult choroidal neovascular membrane due to ARMD. In this particular case OCT could be considered since it offers useful information in the pretreatment and the post-treatment follow-up period.
G P Theodossiadis; V G Grigoropoulos; I Emfietzoglou; P Nikolaidis; D Panagiotidis; I Vergados; P G Theodossiadis
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  European journal of ophthalmology     Volume:  16     ISSN:  1120-6721     ISO Abbreviation:  Eur J Ophthalmol     Publication Date:    2006 May-Jun
Date Detail:
Created Date:  2006-06-08     Completed Date:  2006-08-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9110772     Medline TA:  Eur J Ophthalmol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  491-4     Citation Subset:  IM    
2nd Department of Ophthalmology, Henry Dunant Hospital, Athens, Greece.
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MeSH Terms
Choroidal Neovascularization / drug therapy*,  etiology
Fluorescein Angiography
Macular Degeneration / complications*
Photochemotherapy / adverse effects*
Photosensitizing Agents
Pigment Epithelium of Eye / pathology*
Retinal Detachment / diagnosis,  etiology*
Tomography, Optical Coherence
Reg. No./Substance:
0/Photosensitizing Agents; 0/Porphyrins; 129497-78-5/verteporfin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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