Document Detail


Evolution of phage display: from bioactive peptides to bioselective nanomaterials.
MedLine Citation:
PMID:  18712993     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: New phage-derived biorecognition nanomaterials have emerged recently as a result of the in-depth study of the genetics and structure of filamentous phage and the evolution of phage display technology. OBJECTIVE: This review focuses on the progress made in the development of these new nanomaterials and discusses the prospects of using phage as a bioselectable molecular recognition interface in medical and technical devices. METHODS: The author used data obtained both in his research group and sourced using Science Citation Index (Web of Science) search resources. RESULTS/CONCLUSION: The merging of phage display technologies with nanotechnology over the past few years has proved promising and has already shown its vitality and productivity by contributing vigorously to different areas of medicine and technology, such as medical diagnostics and monitoring, molecular imaging, targeted drug and gene delivery, vaccine development, as well as bone and tissue repair.
Authors:
Va Petrenko
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Expert opinion on drug delivery     Volume:  5     ISSN:  1742-5247     ISO Abbreviation:  Expert Opin Drug Deliv     Publication Date:  2008 Aug 
Date Detail:
Created Date:  2008-08-20     Completed Date:  2008-12-16     Revised Date:  2009-11-17    
Medline Journal Info:
Nlm Unique ID:  101228421     Medline TA:  Expert Opin Drug Deliv     Country:  England    
Other Details:
Languages:  eng     Pagination:  825-36     Citation Subset:  IM    
Affiliation:
Auburn University, Department of Pathobiology, AL 36849, USA. petreva@auburn.edu
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MeSH Terms
Descriptor/Qualifier:
Animals
Biosensing Techniques
Drug Delivery Systems
Drug Discovery
Gene Transfer Techniques
Nanostructures*
Peptide Library*
Peptides / chemistry*
Chemical
Reg. No./Substance:
0/Peptide Library; 0/Peptides

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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