Document Detail

Evolution of lesions in intestinal ischemia.
MedLine Citation:
PMID:  576199     Owner:  NLM     Status:  MEDLINE    
Intestinal ischemia was produced in dogs by ligation and division of a branch of the superior mesenteric artery that supplied a selected segment of bowel. The bowel lesions included patchy mucosal necrosis, ulceration, and stenosis. The development of these changes was studied, and it appeared that ulceration was accompanied by severe submucosal inflammation in uniform appearance. Healing was accomplished by regeneration of mucosa and widespread submucosal fibrosis. Villi developed in the regenerated mucosa about 30 days after the onset of ischemia. Focal disruption of muscularis mucosa and loss of ganglion cells were common, although muscularis propria remained largely intact.
S C Ming; A Bonakdarpour
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Archives of pathology & laboratory medicine     Volume:  101     ISSN:  0003-9985     ISO Abbreviation:  Arch. Pathol. Lab. Med.     Publication Date:  1977 Jan 
Date Detail:
Created Date:  1977-02-16     Completed Date:  1977-02-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7607091     Medline TA:  Arch Pathol Lab Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  40-3     Citation Subset:  AIM; IM    
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MeSH Terms
Collateral Circulation
Intestine, Small / blood supply*,  physiology
Ischemia / etiology,  pathology*
Mucous Membrane / pathology,  physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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