Document Detail

Evolution of left ventricular hypertrophy and function during long-term treatment of systemic hypertension with enalapril.
MedLine Citation:
PMID:  9036764     Owner:  NLM     Status:  MEDLINE    
Continued treatment of hypertensive patients with enalapril reduced left ventricular (LV) hypertrophy steadily over a period of 5 years (by which time gross structural parameters were normal) and produced no further reduction during the following 2 years. Temporary suspension of treatment after 5-year follow-up gave rise to an increase in blood pressure, and to deterioration of LV isovolumic relaxation time and deceleration of the ventricular filling E wave, both of which chiefly reflect the active relaxation of the ventricle.
J R González-Juanatey; A Pose Reino; A V Román; J M García Acuña; J A Fernández López; J C Cerrato
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of cardiology     Volume:  79     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1997 Feb 
Date Detail:
Created Date:  1997-02-27     Completed Date:  1997-02-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  373-6     Citation Subset:  AIM; IM    
Cardiology Department and Hypertension Unit, Complejo Hospitalario Universitario, La Coruna, Spain.
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MeSH Terms
Antihypertensive Agents / therapeutic use*
Echocardiography, Doppler
Enalapril / therapeutic use*
Follow-Up Studies
Hypertension / complications,  drug therapy*,  physiopathology,  ultrasonography
Hypertrophy, Left Ventricular / etiology,  prevention & control*,  ultrasonography
Middle Aged
Time Factors
Treatment Outcome
Ventricular Function, Left / drug effects*
Reg. No./Substance:
0/Antihypertensive Agents; 75847-73-3/Enalapril

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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