| Evolution of genomic instability in diethylnitrosamine-induced hepatocarcinogenesis in mice. | |
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MedLine Citation:
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PMID: 21374661 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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CONCLUSION: Our study suggests that the majority of the current knowledge about genomic changes in HCC is based on advanced tumor lesions and that systematic analyses of the chronologic order including early lesions may reveal new, unexpected findings. |
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Authors:
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Kristina Aleksic; Carolin Lackner; Jochen B Geigl; Martina Schwarz; Martina Auer; Peter Ulz; Maria Fischer; Zlatko Trajanoski; Marcus Otte; Michael R Speicher |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Hepatology (Baltimore, Md.) Volume: 53 ISSN: 1527-3350 ISO Abbreviation: Hepatology Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-03-04 Completed Date: 2011-05-12 Revised Date: 2013-05-20 |
Medline Journal Info:
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Nlm Unique ID: 8302946 Medline TA: Hepatology Country: United States |
Other Details:
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Languages: eng Pagination: 895-904 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 American Association for the Study of Liver Diseases. |
Affiliation:
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Institute of Human Genetics, Medical University of Graz, Graz, Austria. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Carcinoma, Hepatocellular / chemically induced, genetics Comparative Genomic Hybridization Core Binding Factor Alpha 3 Subunit / genetics DNA Copy Number Variations Diethylnitrosamine Genomic Instability* Humans Liver Neoplasms / chemically induced, genetics Male Mice Receptors, Cytoplasmic and Nuclear / genetics beta Catenin / genetics |
| Chemical | |
Reg. No./Substance:
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0/Core Binding Factor Alpha 3 Subunit; 0/Receptors, Cytoplasmic and Nuclear; 0/Runx3 protein, mouse; 0/beta Catenin; 0/nuclear receptor subfamily 0, group B, member 2; 55-18-5/Diethylnitrosamine |
| Comments/Corrections | |
Comment In:
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Hepatology. 2011 Mar;53(3):723-5
[PMID:
21374655
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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