Document Detail


Evolution of bacterial ribosomal protein L1.
MedLine Citation:
PMID:  22450273     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Search vectors composed of Gly, Ala, Arg, and Pro (GARP) residues retrieve 98% of each of the ribosomal proteins in prokaryotic species with no false hits. Different combinations of G, A, R and P and insertions differentiate each ribosomal protein from all others. Amino acids in two sequence positions separate Gram+ from Gram- bacteria. Specific residues separate proteins of cyanobacteria and chloroplasts from all other species. Structural information played an essential role in developing a GARP based technique to achieve perfect sequence alignment. It is possible to understand why GARP residues are 100% conserved in specific positions in families of proteins present in all species.
Authors:
William L Duax; Robert Huether; David Dziak
Related Documents :
6437853 - Inhibition of sea urchin sperm acrosome reaction by antibodies directed against two spe...
2446533 - Evolution and development of the outer acrosomal membrane (oam) and evidence that acros...
6358023 - Cloning and expression of treponema pallidum (nichols) antigen genes in escherichia coli.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of bioinformatics research and applications     Volume:  8     ISSN:  1744-5485     ISO Abbreviation:  Int J Bioinform Res Appl     Publication Date:  2012  
Date Detail:
Created Date:  2012-03-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101253758     Medline TA:  Int J Bioinform Res Appl     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  99-111     Citation Subset:  IM    
Affiliation:
Department of Structural Biology, Hauptman-Woodward Medical Research Institute, 700 Ellicott St., Buffalo, NY 14203, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Computational analysis of adaptive antigenic mutations of the human influenza hemagglutinin for vacc...
Next Document:  Application of nanotechnology in cancer: a review.