Document Detail

Evoked potentials in infant brainstem syndrome associated with Arnold-Chiari malformation.
MedLine Citation:
PMID:  8449379     Owner:  NLM     Status:  MEDLINE    
This study evaluated the contribution of brainstem auditory evoked potentials (BAEPs) and median nerve somatosensory evoked potentials (SEPs) to the assessment of brainstem dysfunction in infants with myelomeningocele and Arnold-Chiari malformation. 16 infants under one year of age were studied. Six had infant brainstem syndrome (IBS). 11 had abnormally prolonged I-V interwave latency (brainstem transmission time, BSTT); BSTT did not differentiate those patients with and without IBS. The cortical 'N20' component of the median-nerve SEPs was absent or had low amplitude and prolonged latency in all six patients with clinical signs of brainstem dysfunction and in four without. Median-nerve SEPs were normal in the patients without IBS. There was a significant difference between patients with and without IBS. Median-nerve SEPs may be a helpful measure of brainstem function in infants with Arnold-Chiari malformation.
A B Barnet; I P Weiss; C Shaer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Developmental medicine and child neurology     Volume:  35     ISSN:  0012-1622     ISO Abbreviation:  Dev Med Child Neurol     Publication Date:  1993 Jan 
Date Detail:
Created Date:  1993-04-12     Completed Date:  1993-04-12     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0006761     Medline TA:  Dev Med Child Neurol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  42-8     Citation Subset:  IM    
George Washington University School of Medicine and Health Sciences, Washington, DC.
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MeSH Terms
Arnold-Chiari Malformation / diagnosis*,  physiopathology
Brain Stem / abnormalities*,  physiopathology
Evoked Potentials, Auditory, Brain Stem*
Evoked Potentials, Somatosensory
Hypoventilation / physiopathology
Median Nerve / physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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