| Evidence for use of mood stabilizers and anticonvulsants in the treatment of nonaffective disorders in children and adolescents. | |
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MedLine Citation:
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PMID: 21079456 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Mood stabilizers and anticonvulsants have been frequently used to control behaviors in children and adolescent with nonaffective disorders. The purpose of this study was to review the literature to evaluate the evidence of these agents as treatment options in this subset of patients. We reviewed all the literature between 1949 and 2009 on the use of anticonvulsants and mood stabilizers in controlling severe behavior dysregulation and aggression in child and adolescent who do not meet the criteria for any mood disorder. The review revealed a total of 19 studies. Of the different mood stabilizers/anticonvulsants, both lithium and divalproex showed some promise in treating children and adolescents with nonmood disorders. Larger studies are nevertheless needed to support the ongoing use of these current anticonvulsants and mood stabilizers in children and adolescents with nonmood disorders. Also, further investigation to the potential use in the long term would need to be established, bearing in mind the balance of side effects and treatment benefit. |
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Authors:
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Alfred Amaladoss; Nasreen Roberts; Franklin Amaladoss |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Clinical neuropharmacology Volume: 33 ISSN: 1537-162X ISO Abbreviation: Clin Neuropharmacol Publication Date: 2010 Nov-Dec |
Date Detail:
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Created Date: 2010-11-16 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7607910 Medline TA: Clin Neuropharmacol Country: United States |
Other Details:
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Languages: eng Pagination: 303-11 Citation Subset: IM |
Affiliation:
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Department of Psychiatry, Hotel Dieu Hospital, Queens University, Ontario, Canada. alfiamaladoss@yahoo.ca |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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