Document Detail


Evidence of trapped red cells in the brain of rhesus monkey infected with Plasmodium knowlesi.
MedLine Citation:
PMID:  6369558     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
59Fe-labelled normal red cells and 51Cr-labelled P. knowlesi infected red cells were used as tracers for a study on the trapped red cells in the brain of rhesus monkeys infected with P. knowlesi. After instantaneous injection into a common carotid artery, blood was sampled from both of the internal jugular veins at various intervals. Results in 6 experiments on 3 infected monkeys showed that about 17% of infected red cells given was trapped in the capillaries of the brain of the infected monkeys. The remainder of the infected red cells travelled on the same flow rate as the normal red cells. As the volume for the flow of the former was less than that of the latter, the mean transit time of the infected red cells (-ty) was therefore shorter than that of the normal red cells (-th). The mean difference in volume was estimated to be 3.4% in the present study. These findings indicated that some of the P. knowlesi infected red cells were trapped in capillaries of the brains of monkeys infected with P. knowlesi.
Authors:
S Areekul; Y Chantachum; C Cheeramakara
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Southeast Asian journal of tropical medicine and public health     Volume:  14     ISSN:  0125-1562     ISO Abbreviation:  Southeast Asian J. Trop. Med. Public Health     Publication Date:  1983 Dec 
Date Detail:
Created Date:  1984-05-22     Completed Date:  1984-05-22     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0266303     Medline TA:  Southeast Asian J Trop Med Public Health     Country:  THAILAND    
Other Details:
Languages:  eng     Pagination:  531-5     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Brain / blood supply
Capillaries
Cerebrovascular Circulation*
Chromium Radioisotopes / diagnostic use
Erythrocytes* / parasitology
Iron Radioisotopes / diagnostic use
Macaca mulatta
Malaria / parasitology,  physiopathology*
Radioisotope Dilution Technique
Chemical
Reg. No./Substance:
0/Chromium Radioisotopes; 0/Iron Radioisotopes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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