| Evidence for a role of the plasma kallikrein-kinin system in acute inflammation: reduced exudation during carrageenin- and kaolin-pleurisies in kininogen-deficient rats. | |
MedLine Citation:
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PMID: 3638906 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Experimental pleurisy was induced by intrapleural injection of carrageenin or kaolin in three strains of rat: Brown Norway-Katholiek (B/N-Ka), Brown Norway-Kitasato (B/N-Ki) and Sprague-Dawley (SD). B/N-Ka rats (kininogen-deficient) showed significantly less pleural fluid accumulation and exudation rate than SD rats or than B/N-Ki rats (normal). The result indicates the involvement of the plasma kallikrein-kinin system in these pleurisies and a role of high-molecular-weight kininogen is suggested. |
Authors:
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S Oh-Ishi; I Hayashi; M Hayashi; K Yamaki; A Yamasu; T Nakano; I Utsunomiya; Y Nagashima |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Agents and actions Volume: 18 ISSN: 0065-4299 ISO Abbreviation: Agents Actions Publication Date: 1986 Jun |
Date Detail:
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Created Date: 1986-09-26 Completed Date: 1986-09-26 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0213341 Medline TA: Agents Actions Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 450-4 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Aging Animals Body Weight Carrageenan Inflammation / enzymology, physiopathology* Kallikreins / metabolism* Kaolin Kininogens / metabolism* Kinins / metabolism* Organ Size Pleurisy / enzymology, physiopathology* Rats Rats, Inbred Strains Species Specificity Tetradecanoylphorbol Acetate |
| Chemical | |
Reg. No./Substance:
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0/Kininogens; 0/Kinins; 1332-58-7/Kaolin; 16561-29-8/Tetradecanoylphorbol Acetate; 9000-07-1/Carrageenan; EC 3.4.21.-/Kallikreins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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