Document Detail


Evidence for prolonged prescribing of aspirin-clopidogrel combination in Scottish primary care.
MedLine Citation:
PMID:  18302308     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To identify whether patients were prescribed the combination of aspirin-clopidogrel in primary care after the generally recommended 12-month period. METHODS: A population based cross-sectional study using data from 61 general practices (1st April 2003-31st March 2004). RESULTS: 691 patients (0.18% of total population) were prescribed aspirin-clopidogrel in combination. 27.78% of these patients had undergone coronary stenting or angioplasty and 34.30% were prescribed this combination for more than 1 year. 96 (13.9%) patients had a previous history of ischaemic stroke or transient ischaemic attack. CONCLUSIONS: Patients were prescribed the combination of aspirin-clopidogrel beyond the generally accepted 12-month period, which may lead to increased safety and cost concerns.
Authors:
Colin R Simpson; Karen Alford; David Williams
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Pharmacoepidemiology and drug safety     Volume:  17     ISSN:  1099-1557     ISO Abbreviation:  Pharmacoepidemiol Drug Saf     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-04-03     Completed Date:  2008-04-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9208369     Medline TA:  Pharmacoepidemiol Drug Saf     Country:  England    
Other Details:
Languages:  eng     Pagination:  397-400     Citation Subset:  IM    
Affiliation:
Department of General Practice & Primary Care, Foresterhill Health Centre, The University of Aberdeen, UK.
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MeSH Terms
Descriptor/Qualifier:
Aged
Aspirin / adverse effects,  therapeutic use*
Cardiovascular Diseases / drug therapy*,  prevention & control
Cross-Sectional Studies
Drug Therapy, Combination
Female
Humans
Male
Platelet Aggregation Inhibitors / therapeutic use*
Population Surveillance / methods
Primary Health Care / statistics & numerical data*
Retrospective Studies
Scotland
Ticlopidine / adverse effects,  analogs & derivatives*,  therapeutic use
Chemical
Reg. No./Substance:
0/Platelet Aggregation Inhibitors; 50-78-2/Aspirin; 55142-85-3/Ticlopidine; 90055-48-4/clopidogrel

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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