Document Detail

Evidence for prescribing exercise as treatment in pediatric rheumatic diseases.
MedLine Citation:
PMID:  20388559     Owner:  NLM     Status:  MEDLINE    
There has been an increasing recognition of adverse short-, mid-, or long-term effects associated with the treatment as well as the disease itself that impair the health-related quality of life and functional capacity of children and adolescents with rheumatic diseases. Interestingly, cumulative evidence has suggested that exercise training may benefit patients with juvenile idiopathic arthritis, juvenile systemic lupus erythematosus, juvenile dermatomyositis and juvenile fibromyalgia, attenuating several clinical symptoms related to physical disability. Remarkably, recent evidence also suggests that exercise may have direct effects on the pathogenesis of autoimmune diseases by attenuating chronic low-grade systemic inflammation. It is also important to emphasize that no exercise-related adverse effects have been reported. This short review provides the evidence for physical training as a treatment of pediatric rheumatic diseases, introducing a novel concept that exercise is a treatment for these populations.
Bruno Gualano; Ana Lucia Sá Pinto; Beatriz Perondi; Danilo Marcelo Leite Prado; Clarissa Omori; Roberta Tavares Almeida; Adriana Maluf Elias Sallum; Clovis Artur Almeida Silva
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2010-04-11
Journal Detail:
Title:  Autoimmunity reviews     Volume:  9     ISSN:  1873-0183     ISO Abbreviation:  Autoimmun Rev     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-06-01     Completed Date:  2010-08-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101128967     Medline TA:  Autoimmun Rev     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  569-73     Citation Subset:  IM    
Copyright Information:
Copyright 2010 Elsevier B.V. All rights reserved.
Universidade de São Paulo, School of Physical Education and Sports, Brazil.
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MeSH Terms
Clinical Trials as Topic
Exercise Therapy*
Rheumatic Diseases / immunology,  rehabilitation*,  therapy*

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