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Evidence for oxygen use in preterm infants.
MedLine Citation:
PMID:  22404889     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Aim:  To review the evidence for optimal oxygen use in preterm infants. Results:  Clinicians have embraced lower saturation targets to minimize retinopathy of prematurity (ROP). Large randomized trials now have shown that while such targets reduce ROP, neonatal mortality is increased significantly. Conclusions:  Preterm infants should be resuscitated with blended oxygen (30-90%) targeted to avoid hyperoxia. Later, saturation management remains uncertain. Until ongoing trials and follow-up are complete, it is prudent to avoid saturation of 85-89%.
Authors:
Monuj Triven Bashambu; Monika Bhola; Michele Walsh
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta paediatrica (Oslo, Norway : 1992). Supplement     Volume:  101     ISSN:  0803-5326     ISO Abbreviation:  Acta Paediatr Suppl     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-03-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9315043     Medline TA:  Acta Paediatr Suppl     Country:  Norway    
Other Details:
Languages:  eng     Pagination:  29-33     Citation Subset:  IM    
Copyright Information:
© 2012 The Author(s)/Acta Paediatrica © 2012 Foundation Acta Paediatrica.
Affiliation:
Division of Neonatology, Rainbow Babies & Childrens Hospital, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH, USA.
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