Document Detail

Evidence for the optical signalling of changes in bicarbonate concentration within the mitochondrial region of living cells.
MedLine Citation:
PMID:  21637866     Owner:  NLM     Status:  MEDLINE    
Image and spectral intensity from bicarbonate-selective europium(III) probes localised in the mitochondria of cells is modulated reversibly by variation of external pCO(2), and is suppressed by addition of the carbonic anhydrase inhibitor, acetazolomide.
David G Smith; Ga-lai Law; Benjamin S Murray; Robert Pal; David Parker; Ka-Leung Wong
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2011-06-02
Journal Detail:
Title:  Chemical communications (Cambridge, England)     Volume:  47     ISSN:  1364-548X     ISO Abbreviation:  Chem. Commun. (Camb.)     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-06-21     Completed Date:  2011-10-17     Revised Date:  2014-02-20    
Medline Journal Info:
Nlm Unique ID:  9610838     Medline TA:  Chem Commun (Camb)     Country:  England    
Other Details:
Languages:  eng     Pagination:  7347-9     Citation Subset:  IM    
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MeSH Terms
Bicarbonates / metabolism*
Biological Transport
Cell Line
Cell Survival
Mitochondria / metabolism*
Optical Processes*
Grant Support
266804//European Research Council
Reg. No./Substance:

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