Document Detail


Evidence for modality-specific but not frequency-specific modulation of human primary auditory cortex by attention.
MedLine Citation:
PMID:  20547217     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We used the stimulus-driven 40-Hz auditory steady-state response (ASSR) that localizes tonotopically to the region of primary auditory cortex (A1) to study modulation of this region by top-down attention. Experiment 1 presented amplitude modulated (AM) auditory and visual stimuli simultaneously (AM at 40 Hz and 16 Hz, respectively) while participants responded to targets in one modality or the other. ASSR amplitude increased from an unattended passive baseline during auditory but not visual attention demonstrating modality-specific auditory attention, when attention was required for brief (1 s) but not long (2 min) time intervals. Modality-specific visual attention occurred at both time intervals. Experiment 2 asked whether attention directed to one or the other of two simultaneous auditory streams (carrier frequencies of 250 and 4100 Hz AM at 37 and 41 Hz respectively, counterbalanced) increased ASSR amplitude for the attended stream (frequency-specific auditory attention). Behaviour was strongly controlled by carrier frequency (overall target rate 1.7 Hz), and the cortical sources of the two carriers were resolved by inverse modeling. Despite these conditions favourable to frequency specificity, frequency-specific modulation of ASSR amplitude was not found at either time interval. Frequency-specific modulation of A1 may require re-entrant feedback to the auditory core from auditory percepts that possess distinct spectral attributes and are attended in higher regions of the auditory system.
Authors:
P E Gander; D J Bosnyak; L E Roberts
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-06-12
Journal Detail:
Title:  Hearing research     Volume:  268     ISSN:  1878-5891     ISO Abbreviation:  Hear. Res.     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-08-17     Completed Date:  2010-12-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7900445     Medline TA:  Hear Res     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  213-26     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2010 Elsevier B.V. All rights reserved.
Affiliation:
Department of Psychology, Neuroscience, and Behaviour McMaster University, Hamilton, Ontario, Canada. pgander@mcmaster.ca
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MeSH Terms
Descriptor/Qualifier:
Acoustic Stimulation
Adolescent
Adult
Attention*
Audiometry, Pure-Tone
Auditory Cortex / physiology*
Auditory Pathways / physiology*
Auditory Perception*
Electroencephalography
Feedback, Psychological
Female
Humans
Male
Photic Stimulation
Psychoacoustics
Reaction Time
Time Factors
Young Adult
Grant Support
ID/Acronym/Agency:
//Canadian Institutes of Health Research

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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