Document Detail

Evidence of increased motoneuron excitability in stroke patients without clinical spasticity.
MedLine Citation:
PMID:  18794219     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION: The contribution of hyperreflexia to impairment after stroke is debated. Spinal motoneuron excitability in healthy subjects and stroke patients with and without spasticity was compared. METHODS: Twenty-four patients with single stroke more than 6 months ago and 18 gender-matched healthy volunteers were included. Spasticity was assessed according to the Modified Ashworth Scale. Mmax amplitude and F wave frequency in the abductor pollicis brevis muscle were measured by electrical stimulation of the median nerve. RESULTS: Mmax values were comparable between the groups. However, patients with (n=7) and without (n=17) clinically evident spasticity had a significant increase in F wave frequency when compared with healthy subjects. F wave frequency did not differ between spastic and nonspastic patients. DISCUSSION: Increase in spinal motoneuron excitability after stroke is present in stroke patients with minor or no motor deficiencies and does not necessarily lead to spasticity.
Jakob Udby Blicher; Jørgen Feldbaek Nielsen
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Publication Detail:
Type:  Journal Article     Date:  2008-09-15
Journal Detail:
Title:  Neurorehabilitation and neural repair     Volume:  23     ISSN:  1545-9683     ISO Abbreviation:  Neurorehabil Neural Repair     Publication Date:  2009 Jan 
Date Detail:
Created Date:  2008-12-25     Completed Date:  2009-03-05     Revised Date:  2009-10-15    
Medline Journal Info:
Nlm Unique ID:  100892086     Medline TA:  Neurorehabil Neural Repair     Country:  United States    
Other Details:
Languages:  eng     Pagination:  14-6     Citation Subset:  IM    
Hammel Neurorehabilitation and Research Centre, Aarhus University Hospital, Hammel, Denmark.
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MeSH Terms
Action Potentials / physiology
Brain / pathology,  physiopathology
Electric Stimulation
Electrodiagnosis / methods
Median Nerve / physiopathology
Middle Aged
Motor Neurons / physiology*
Muscle Contraction / physiology
Muscle Spasticity / diagnosis*,  etiology,  physiopathology*
Muscle, Skeletal / innervation,  physiopathology
Neural Conduction / physiology
Predictive Value of Tests
Reflex, Abnormal / physiology*
Spinal Cord / physiopathology*
Stroke / complications,  physiopathology*
Comment In:
Neurorehabil Neural Repair. 2009 Oct;23(8):870; author reply 870-1   [PMID:  19675124 ]

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