Document Detail

Evidence for fusimotor drive in stroke patients based on muscle spindle thixotropy.
MedLine Citation:
PMID:  10320026     Owner:  NLM     Status:  MEDLINE    
To study fusimotor function in stroke patients, we compared the amplitude of stretch reflexes elicited in flexor carpi radialis (FCR) after contraction of FCR with the wrist held flexed ('hold-short') or extended ('hold-long'). Seven subjects with impaired hand function and spasticity due to stroke, and seven healthy subjects were investigated. Surface electrodes recorded electromyographic activity of wrist flexors and extensors while subjects performed isometric wrist flexions with the wrist alternately in 15 degrees of flexion or extension. After contractions the wrist was moved passively to the mid-position, and stretch reflexes were elicited via controlled mechanical taps delivered over the FCR tendon. For both groups, the amplitude of the stretch reflex was greater after 'hold-short' than 'hold-long' contractions. This finding is consistent with the 'after-effects' of intrafusal fibre activation, and suggests that fusimotor neurones are activated during voluntary contractions of the paretic limb, just as in the limb of a healthy subject.
L R Wilson; J M Gracies; D Burke; S C Gandevia
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Neuroscience letters     Volume:  264     ISSN:  0304-3940     ISO Abbreviation:  Neurosci. Lett.     Publication Date:  1999 Apr 
Date Detail:
Created Date:  1999-06-17     Completed Date:  1999-06-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7600130     Medline TA:  Neurosci Lett     Country:  IRELAND    
Other Details:
Languages:  eng     Pagination:  109-12     Citation Subset:  IM    
Prince of Wales Medical Research Institute, Prince of Wales Hospital, University of New South Wales, Sydney, Australia.
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MeSH Terms
Cerebrovascular Disorders / complications,  physiopathology*
Hand / physiopathology
Isometric Contraction / physiology
Middle Aged
Motor Neurons, Gamma / physiology*
Muscle Spasticity / etiology
Muscle Spindles / physiopathology*
Muscle, Skeletal / physiopathology
Physical Stimulation
Posture / physiology
Reflex, Stretch / physiology
Wrist / physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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