| Evidence of carotid atherosclerosis in orthopantomograms and the risk for future cardiovascular events. | |
| | |
MedLine Citation:
|
PMID: 21104618 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Evidence of carotid atherosclerosis can be detected in 3 to 5% of orthopantomogram (OPG) investigations. The clinical impact of these findings is unknown. We investigated the association of OPG findings of carotid atherosclerosis with the occurrence of future cardiovascular adverse events. PATIENTS AND METHODS: We randomly selected 411 of 1268 participants with pre-existent cardiovascular disease from the prospective Inflammation in Carotid Arteries Risk for Arthrosclerosis Study (ICARAS) and assessed their OPGs for the presence of calcified atherosclerotic lesions or indirect signs of atherosclerosis, such as surgical clips or intravascular stents. The degree of carotid stenosis was measured by duplex ultrasound investigations. Patients were then followed for median 39 months (interquartile range 33 to 44 months) for the occurrence of major adverse cardiovascular events (MACE) including myocardial infarction, coronary revascularisation, stroke and death. RESULTS: We found no statistically significant association between the presence of carotid atherosclerosis detected on OPGs and the presence of a significant carotid stenosis (left carotid artery kappa=0.08; right carotid artery kappa=0.12), or the degree of carotid stenosis (P=0.20). Furthermore, the presence of OPG signs of carotid atherosclerosis was not statistically significant associated with future MACE (adjusted hazard ratio 0.92, 95% confidence interval 0.59 to 1.42; P=0.70). CONCLUSIONS: Evidence of carotid plaque revealed by OPGs in patients with previously known cardiovascular disease is no useful prognostic marker for MACE. Detection of carotid atherosclerosis by OPGs in these patients therefore has no clinical consequence. |
| | |
Authors:
|
M Hoke; B Schmidt; T Schillinger; W Kluger; F Wiesbauer; W Mlekusch; E Minar; M Schillinger |
Related Documents
:
|
11571968 - Management of penetrating injuries to carotid artery. 17596998 - External carotid artery stenosis in patients with head and neck squamous cell carcinoma... 11839848 - J.l. corning and vagal nerve stimulation for seizures in the 1880s. 9971908 - Side-to-side differences of the common carotid artery diameter in presence of asymmetry... 22329708 - Parachute mitral valve with severe mitral regurgitation in an adult patient. 17681088 - A congenital fistula between the descending aorta and the right pulmonary vein in a neo... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: VASA. Zeitschrift für Gefässkrankheiten Volume: 39 ISSN: 0301-1526 ISO Abbreviation: VASA Publication Date: 2010 Nov |
Date Detail:
|
Created Date: 2010-11-24 Completed Date: 2011-01-14 Revised Date: 2012-10-19 |
Medline Journal Info:
|
Nlm Unique ID: 0317051 Medline TA: Vasa Country: Switzerland |
Other Details:
|
Languages: eng Pagination: 298-304 Citation Subset: IM |
Affiliation:
|
General Hospital Vienna, Internal Medicine II/Angiology, Medical University Vienna, Vienna, Austria. matthias.hoke@meduniwien.ac.at |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Austria Cardiovascular Diseases / etiology*, mortality Carotid Artery Diseases / complications, mortality, radiography*, ultrasonography Carotid Stenosis / complications, mortality, radiography*, ultrasonography Chi-Square Distribution Female Humans Kaplan-Meier Estimate Male Middle Aged Predictive Value of Tests Prognosis Proportional Hazards Models Prospective Studies Radiography, Panoramic* Risk Assessment Risk Factors Severity of Illness Index Time Factors Ultrasonography, Doppler, Duplex |
| Comments/Corrections | |
Comment In:
|
Vasa. 2011 Jan;40(1):82-3; athor reply 84
[PMID:
21283979
]
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Venous pressure gradients in the lower extremity and the hemodynamic consequences.
Next Document: Characteristics of prevalence in peripheral arterial disease and correlative risk factors and comorb...