Document Detail


Evidence-based practice: how to perform and use systematic reviews for clinical decision-making.
MedLine Citation:
PMID:  20523217     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
One approach to clinical decision-making requires the integration of the best available research evidence with individual clinical expertise and patient values, and is known as evidence-based medicine (EBM). In clinical decision-making with the current best evidence, systematic reviews have an important role. This review article covers the basic principles of systematic reviews and meta-analyses, and their role in the process of evidence-based decision-making. The problems associated with traditional narrative reviews are discussed, as well as the way systematic reviews limit bias associated with the assembly, critical appraisal and synthesis of studies addressing specific clinical questions. The relevant steps in writing a systematic review from the formulation of an initial research question to sensitivity analyses in conjunction with the combined analysis of the pooled data are described. Important issues that need to be considered when appraising a systematic review or meta-analysis are outlined. Some of the terms that are used in the reporting of systematic reviews and meta-analyses, such as relative risk, confidence interval, Forest plot or L'Abbé plot, will be introduced and explained.
Authors:
Peter Kranke
Related Documents :
19074247 - What is lost when searching only one literature database for articles relevant to injur...
15925067 - Urine markers for bladder cancer surveillance: a systematic review.
16687357 - Evidence-based pain management and palliative care in issue three for 2005 of the cochr...
25041887 - Total hip arthroplasty in hiv-seropositive patients - case study and review of literature.
21711957 - Bronchitis (acute).
15007377 - Unusual stab injury of the spinal cord.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of anaesthesiology     Volume:  27     ISSN:  1365-2346     ISO Abbreviation:  Eur J Anaesthesiol     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-08-03     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8411711     Medline TA:  Eur J Anaesthesiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  763-72     Citation Subset:  IM    
Affiliation:
Department of Anaesthesia and Critical Care, University Hospital of Würzburg, Würzburg, Germany. kranke_p@klinik.uni-wuerzburg.de
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Prehypoxic clonidine administration improves vasomotricity of isolated rat aorta during reoxygenatio...
Next Document:  Airway management and supraglottic devices: which solution for which problem?