Document Detail

Evidence-based medicine and health economics: a case study of end stage renal disease.
MedLine Citation:
PMID:  10862077     Owner:  NLM     Status:  MEDLINE    
This paper explores the potential for use of an economic evaluation framework alongside systematic reviews. Clinical issues in dialysis therapy for end stage renal disease are used as case studies. The effectiveness data required were obtained from a systematic review of randomized controlled trials. Resource use and cost data were obtained from three sources; the identified randomized controlled trials, a separate review of observational studies and primary data collection. The results of the case studies show that, although simple economic evaluations were possible, issues arose, such as how transferable results are between settings and how appropriate it is to focus on the average patient. The interface between economic evaluation and systematic reviews needs to be further developed in order to ensure that the best available evidence can be used to inform future policy and research.
L Vale; C Donaldson; C Daly; M Campbell; J Cody; A Grant; I Khan; P Lawrence; S Wallace; A MacLeod
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Health economics     Volume:  9     ISSN:  1057-9230     ISO Abbreviation:  Health Econ     Publication Date:  2000 Jun 
Date Detail:
Created Date:  2000-08-30     Completed Date:  2000-08-30     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9306780     Medline TA:  Health Econ     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  337-51     Citation Subset:  IM    
Copyright Information:
Copyright 2000 John Wiley & Sons, Ltd.
Health Economics Research Unit, University of Aberdeen, UK.
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MeSH Terms
Chi-Square Distribution
Cost-Benefit Analysis
Evidence-Based Medicine*
Health Services Research
Kidney Failure, Chronic / economics*,  therapy
Outcome Assessment (Health Care)*
Randomized Controlled Trials as Topic / economics*
Renal Dialysis / methods
Research Design

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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