Document Detail

Evidence-based medicine: arguments for and against.
MedLine Citation:
PMID:  16091092     Owner:  NLM     Status:  MEDLINE    
In this article I will discuss the various definitions of evidence-based medicine (EBM), and summarize the application, criticisms and limitations of EBM. The spectrum of evidence, from pathophysiological inference to randomized controlled trials, will be presented as a mechanism for filtering bias with more rigorous evidence being required when bias is more likely. Although randomized controlled trials and meta-analyses are at the top of the evidence hierarchy, they are not always necessary, might not be the most appropriate forms of evidence for some clinical questions, and have their own limitation that need to be understood. Best available evidence, applied to individual patients, is the corner stone of EBM. Although there are valid criticisms and limitations of EBM, if these are understood then the practice of EBM can provide guidance to the clinician and enhance patient care.
Steven Doherty
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Emergency medicine Australasia : EMA     Volume:  17     ISSN:  1742-6731     ISO Abbreviation:  Emerg Med Australas     Publication Date:  2005 Aug 
Date Detail:
Created Date:  2005-08-10     Completed Date:  2006-01-20     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  101199824     Medline TA:  Emerg Med Australas     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  307-13     Citation Subset:  IM    
Emergency Department, Tamworth Base Hospital, Tamworth, New South Wales, Australia.
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MeSH Terms
Attitude of Health Personnel
Evidence-Based Medicine / methods,  organization & administration*
Health Knowledge, Attitudes, Practice
Organizational Culture
Professional Practice / organization & administration
Quality of Health Care / organization & administration
Research Design
Terminology as Topic
Comment In:
Emerg Med Australas. 2005 Aug;17(4):297-8   [PMID:  16091088 ]

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