Document Detail

Evidence for the Likely Origin of Homochirality in Amino Acids, Sugars, and Nucleosides on Prebiotic Earth.
MedLine Citation:
PMID:  22444622     Owner:  NLM     Status:  Publisher    
Over the past century the origin of terrestrial prebiotic homochirality has been the subject of many speculations. For life to start on earth and elsewhere, it is critical that the building blocks of amino acids, sugars, and nucleosides be created in predominant homochiral form. Recent findings of a modest excess L chirality of α-methylamino acids in some meteorites that landed on earth have furnished an important piece of evidence. We have shown how these meteoritic components can furnish normal L amino acids, and therefrom D sugars and nucleosides, in high chiral excess under sensible prebiotic conditions. Some important remaining goals are also described.
Ronald Breslow
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-3-25
Journal Detail:
Title:  Journal of the American Chemical Society     Volume:  -     ISSN:  1520-5126     ISO Abbreviation:  -     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-3-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7503056     Medline TA:  J Am Chem Soc     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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