| Evidence for a dose-dependent effect of pulsed magnetic fields on pain processing. | |
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MedLine Citation:
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PMID: 20643187 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Functional magnetic resonance imaging (fMRI) was used to investigate the dose-response relationship (sham, 100, 200, 1000 microT) between a pulsed extremely low frequency magnetic field (ELFMF) and acute thermal pain on the dominant right hand. Forty-seven participants were recruited, and pulsed ELFMF was applied through the MRI gradient system using a novel technique. Regions of interest (ROIs) matching those of previous studies were examined for a potential dose response. Significant correlations between applied field strength and change in BOLD activity were found in the anterior cingulate and the ipsilateral insula, indicating that there might be either a dose response or a threshold effect of the ELFMF. |
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Authors:
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John A Robertson; Nicole Juen; Jean Théberge; Julie Weller; Dick J Drost; Frank S Prato; Alex W Thomas |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-07-17 |
Journal Detail:
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Title: Neuroscience letters Volume: 482 ISSN: 1872-7972 ISO Abbreviation: Neurosci. Lett. Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-08-20 Completed Date: 2010-12-06 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7600130 Medline TA: Neurosci Lett Country: Ireland |
Other Details:
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Languages: eng Pagination: 160-2 Citation Subset: IM |
Copyright Information:
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(c) 2010 Elsevier Ireland Ltd. All rights reserved. |
Affiliation:
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Imaging Program, Lawson Health Research Institute, London, ON, Canada. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Adult Brain / physiopathology, radiation effects* Brain Mapping Dose-Response Relationship, Radiation Electromagnetic Fields* Humans Magnetic Resonance Imaging Pain / physiopathology* Pain Perception Temperature Young Adult |
| Grant Support | |
ID/Acronym/Agency:
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//Canadian Institutes of Health Research |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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