| Update: Use of platelet glycoprotein IIb/IIIa inhibitors in patients with unstable angina and non-ST-segment elevation myocardial infarction. | |
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MedLine Citation:
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PMID: 20646787 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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DATA SOURCES: Searches were conducted of MEDLINE (1966 to 2006), EMBASE (1980 to April 2006), and the Cochrane's CENTRAL register (Issue 2, 2006), and hand-searched information from cardiology conferences, principal investigators of identified trials, pharmaceutical manufacturers, and other experts in the field were used. There were no language restrictions. STUDY SELECTION: Randomized controlled trials enrolling patients with non-ST-segment elevation acute coronary syndromes who initially received GPIIb/IIa inhibitors as part of the early medical management were eligible. DATA EXTRACTION AND SYNTHESIS: Primary outcomes were 30-day and 6-month mortality and the subsequent development of myocardial infarction; the secondary endpoint was major hemorrhage, defined as intracranial bleeding or any bleeding with a decrease in hemoglobin of greater than 5 g/dL or a greater than 15% reduction in hematocrit level. Data were reported as odds ratios (ORs) with a fixed-effect model if minimal heterogeneity was identified; otherwise, a random-effects model was used. All analyses were presented as intention to treat. |
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Authors:
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Maude Latulippe; Eddy S Lang |
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Publication Detail:
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Type: Comment; Journal Article Date: 2010-06-19 |
Journal Detail:
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Title: Annals of emergency medicine Volume: 56 ISSN: 1097-6760 ISO Abbreviation: Ann Emerg Med Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-11-01 Completed Date: 2010-11-12 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8002646 Medline TA: Ann Emerg Med Country: United States |
Other Details:
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Languages: eng Pagination: e1-2 Citation Subset: - |
Copyright Information:
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Copyright © 2010 American College of Emergency Physicians. Published by Mosby, Inc. All rights reserved. |
Affiliation:
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University of Calgary, Faculty of Medicine, Division of Emergency Medicine Foothills Medical Centre, Calgary, Alberta, Canada. |
Export Citation:
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Descriptor/Qualifier:
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| Comments/Corrections | |
Comment On:
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Cochrane Database Syst Rev. 2010;(9):CD002130
[PMID:
20824831
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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