Document Detail


Evasion of natural killer cells by influenza virus.
MedLine Citation:
PMID:  20682623     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
NK cells are important innate immune effectors during influenza virus infection. However, the influenza virus seems able to use several tactics to counter NK cell recognition for immune evasion. In this review, we will summarize and discuss recent advances regarding the understanding of NK cell evasion mechanisms manipulated by the influenza virus to facilitate its rapid replication inside the respiratory epithelial cells.
Authors:
Hailong Guo; Pawan Kumar; Subramaniam Malarkannan
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review     Date:  2010-08-03
Journal Detail:
Title:  Journal of leukocyte biology     Volume:  89     ISSN:  1938-3673     ISO Abbreviation:  J. Leukoc. Biol.     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-02-01     Completed Date:  2011-03-21     Revised Date:  2012-02-01    
Medline Journal Info:
Nlm Unique ID:  8405628     Medline TA:  J Leukoc Biol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  189-94     Citation Subset:  IM    
Affiliation:
Department of Microbiology and Immunology, University of Rochester, Rochester, New York, USA. hailong_guo@urmc.rochester.edu
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MeSH Terms
Descriptor/Qualifier:
Humans
Immune Evasion*
Influenza A virus / immunology*
Influenza, Human / immunology*,  pathology,  virology*
Killer Cells, Natural / immunology*,  pathology
Grant Support
ID/Acronym/Agency:
R01 A1064826-01//PHS HHS

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