| Evans syndrome: a study of six cases with review of literature. | |
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MedLine Citation:
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PMID: 19055865 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Evans syndrome is an uncommon condition characterised by simultaneous or sequential development of immune thrombocytopenia (ITP) and autoimmune haemolytic anaemia (AIHA) with a positive direct antiglobulin test (DAT) in the absence of a known underlying aetiology. The great majority of patients with Evans syndrome have a chronic relapsing course despite treatment, which is associated with significant morbidity and mortality. We reviewed the clinical and laboratory features of six patients with Evans syndrome. All patients had thrombocytopenia, bleeding symptoms and haemolytic anaemia with positive direct Coombs test at presentation. We discuss the aetiopathogenic, clinical, therapeutic and natural history of Evans syndrome. |
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Authors:
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Kajal Kiran Dhingra; Deepali Jain; Shramana Mandal; Nita Khurana; Tejinder Singh; Naresh Gupta |
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Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: Hematology (Amsterdam, Netherlands) Volume: 13 ISSN: 1607-8454 ISO Abbreviation: Hematology Publication Date: 2008 Dec |
Date Detail:
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Created Date: 2008-12-05 Completed Date: 2009-02-27 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9708388 Medline TA: Hematology Country: England |
Other Details:
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Languages: eng Pagination: 356-60 Citation Subset: IM |
Affiliation:
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Department of Pathology, Maulana Azad Medical College and Lok Nayak Hospital, Bahadur Shah Zafar Marg, New Delhi 110002, India. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Anemia, Hemolytic, Autoimmune*
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etiology,
pathology,
therapy Coombs' Test Humans Purpura, Thrombocytopenic, Idiopathic* / etiology, pathology, therapy Syndrome |
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