Document Detail

Evaluation with equilibrium radionuclide angiography of left ventricular systolic and diastolic function in pulmonary hypertension secondary to chronic pulmonary diseases.
MedLine Citation:
PMID:  2636288     Owner:  NLM     Status:  MEDLINE    
To evaluate left ventricular systolic and diastolic function in patients with pulmonary hypertension secondary to chronic pulmonary diseases, 86 patients were studied using equilibrium radionuclide angiography with forward and reverse gating from the R wave. At rest left ventricular function, both in systolic and diastolic properties, in patients with pulmonary hypertension was significantly lower than in normal subjects (LVEF; P less than 0.05, PER; p less than 0.05, PFR; P less than 0.025, FF; P less than 0.025). During exercise left ventricular systolic function did not increase as much as in normals (LVEF; N.S., PER; N.S.). Left ventricular diastolic function during exercise was significantly lower than at rest (PFR; P less than 0.05, FF; P less than 0.001). The indices of left ventricular function obtained from radionuclide angiography had no close correlation with pulmonary hemodynamics or with blood gases. These results demonstrated that left ventricular dysfunction in patients with pulmonary hypertension was observed both at rest and during exercise, and might play an important role in reduced exercise tolerance.
K Inoue; K Sera; H Fukuzaki
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Kobe journal of medical sciences     Volume:  35     ISSN:  0023-2513     ISO Abbreviation:  Kobe J Med Sci     Publication Date:  1989 Aug 
Date Detail:
Created Date:  1990-06-27     Completed Date:  1990-06-27     Revised Date:  2008-04-08    
Medline Journal Info:
Nlm Unique ID:  0413531     Medline TA:  Kobe J Med Sci     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  239-54     Citation Subset:  IM    
National Akashi Hospital, Japan.
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MeSH Terms
Gated Blood-Pool Imaging
Heart Ventricles / physiopathology
Hypertension, Pulmonary / etiology,  physiopathology*
Lung Diseases, Obstructive / complications
Middle Aged
Tuberculosis, Pulmonary / complications

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