Document Detail


Evaluation of volumetric measurements in patients with acute type B aortic dissection--thoracic endovascular aortic repair (TEVAR) vs conservative.
MedLine Citation:
PMID:  18986789     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: The aim of this retrospective study was to evaluate aortic volume changes in patients with acute type B aortic dissection (TBD), treated either by thoracic endovascular aortic repair (TEVAR) or conservatively.
MATERIALS AND METHODS: From July 1996 through March 2008, 76 patients presenting with acute TBD were referred to our department. To ensure a follow-up of at least 24 months, only 64 of them were included in the present study, with the cut-off for inclusion being March 2006. Twenty-nine of these patients underwent TEVAR and 35 patients underwent conservative treatment. Indications for TEVAR were life-threatening symptoms. Follow-up was performed postinterventionally in patients after TEVAR and at 3, 6, and 12 months, and yearly thereafter in both groups. It included clinical examinations, computed tomography (CT) scans, analysis of volume changes in true thoracic lumen (TTL), false thoracic lumen (FTL), thoracic lumen (TL), abdominal lumen (AL), and aortic diameter measurements. In addition, the extent of thrombosis and its influence on volume changes were assessed.
RESULTS: Mean follow-up was 41 months after TEVAR and 46 months in the conservatively-treated patients. At 60 months, cumulative rates of freedom from dissection-related death and rupture-free survival were 82.6% and 93.1% in the TEVAR group, respectively. They were 74.9% and 88.5% in the conservatively-treated group, respectively. In the conservatively-treated patients, 3 patients died of late aortic rupture, 4 were converted to open surgery, and 2 to TEVAR. Evaluation of volume changes showed better results in the TEVAR group within 24 months. However, within 60 months the difference between the two groups was no longer relevant. Relating to thrombosis of the FTL, analyses showed slightly better overall results and promotion of thrombus formation after TEVAR. However, at 60 months the results showed a tendency towards approximation between the two groups.
CONCLUSION: Our data suggest that TEVAR seems to delay the natural course of the disease but not to stop it.
Authors:
Iris Eva Chemelli-Steingruber; Andreas Chemelli; Alexander Strasak; Beate Hugl; Renate Hiemetzberger; Benedikt V Czermak
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2008-11-04
Journal Detail:
Title:  Journal of vascular surgery     Volume:  49     ISSN:  1097-6809     ISO Abbreviation:  J. Vasc. Surg.     Publication Date:  2009 Jan 
Date Detail:
Created Date:  2009-01-28     Completed Date:  2009-02-19     Revised Date:  2012-10-03    
Medline Journal Info:
Nlm Unique ID:  8407742     Medline TA:  J Vasc Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  20-8     Citation Subset:  IM    
Affiliation:
Department of Radiology, Innsbruck Medical University, Innsbruck, Austria.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Aneurysm, Dissecting / complications,  mortality,  radiography*,  surgery*
Angiography, Digital Subtraction
Aorta, Thoracic / radiography*,  surgery*
Aortic Aneurysm, Thoracic / complications,  mortality,  radiography*,  surgery*
Aortic Rupture / etiology,  radiography,  surgery
Aortography / methods
Blood Vessel Prosthesis Implantation*
Dilatation, Pathologic
Disease Progression
Female
Humans
Male
Middle Aged
Radiographic Image Interpretation, Computer-Assisted
Retrospective Studies
Thrombosis / etiology,  radiography,  surgery
Time Factors
Tomography, Spiral Computed
Treatment Outcome

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