Document Detail

Evaluation of use of herbal medicines among ambulatory hypertensive patients attending a secondary health care facility in Nigeria.
MedLine Citation:
PMID:  20214258     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: The aim was to evaluate use of herbal medicine among hypertensive patients. METHOD: The study was carried out at a secondary health care facility in Maiduguri, Nigeria, between April and June 2007. Pretested questionnaires were administered to 500 ambulatory hypertensive patients attending the hypertension clinic after giving consent. Demographic data of respondents, information on reasons for use, sources of herbal medicines, co-administration with allopathic agents, effects observed, steps taken when adverse effects were observed and reasons for discontinuation of herbal medicines were obtained. Data were analysed using descriptive statistics and chi2 at a significance level of P < 0.05. KEY FINDINGS: One hundred and twenty respondents were found to be using herbal medicines. Increased age was associated with increased use of herbal medicines (P < 0.05). Co-administration of herbal medicines with antihypertensive agents was done by 47.5% respondents, out of which herbs with antihypertensive activity were used by 33.33%. The majority of respondents, 71.15%, were using herbal medicines unbeknownst to their physicians. Clinically evident adverse effects due to co-administration of herbal medicines and allopathic agents were reported by 21.04% of the respondents. Side effects observed (3.79%), improvement in clinical conditions (3.03%), perceived inefficacy of the herbal medicine (1.52%) and instructions by the health care provider (21.15%) were reasons given for discontinuation of the herbal medicines. Reasons given for preferring herbal medicines were combinations of perceived failure of allopathic medicines (31.73%), relatively high cost of allopathic medicine (23.08%), socio-cultural practices/herbal knowledge (20.19%), poor accessibility to medical facilities (19.23%), safety concerns (9.62%) and uncaring attitudes of hospital staff when attending to respondents (6.73%). CONCLUSIONS: Herbal medicines were often co-administered with allopathic agents by hypertensive patients, and health care givers need to be vigilant and include questions about use of herbal medicines when taking a patient's drug medication history.
Nwako S Olisa; Fakeye T Oyelola
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The International journal of pharmacy practice     Volume:  17     ISSN:  0961-7671     ISO Abbreviation:  Int J Pharm Pract     Publication Date:  2009 Apr 
Date Detail:
Created Date:  2010-03-10     Completed Date:  2010-03-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9204243     Medline TA:  Int J Pharm Pract     Country:  England    
Other Details:
Languages:  eng     Pagination:  101-5     Citation Subset:  IM    
Department of Clinical Pharmacy and Pharmacy Administration, University of Ibadan, Ibadan, Nigeria.
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MeSH Terms
Age Factors
Aged, 80 and over
Ambulatory Care Facilities
Antihypertensive Agents / therapeutic use
Herb-Drug Interactions
Hypertension / drug therapy*
Middle Aged
Nigeria / epidemiology
Phytotherapy / adverse effects,  utilization*
Plant Extracts / adverse effects,  therapeutic use*
Young Adult
Reg. No./Substance:
0/Antihypertensive Agents; 0/Plant Extracts

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