Document Detail


Evaluation of the upper esophageal sphincter (UES) using simultaneous high-resolution endoluminal sonography (HRES) and manometry.
MedLine Citation:
PMID:  15259487     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The aim of this study was to characterize the motion, morphology, and pressure of the upper esophageal sphincter (UES). The UES and its surrounding structures were evaluated in seven normal subjects and four human cadavers, using simultaneous high-resolution endoluminal sonography and manometry. The UES musculature on ultrasound is a C-shaped structure with an angle of 107 +/- 19 degrees. The mean peak resting UES pressure was 74 mm Hg, with a total cross-sectional area (CSA) of 0.87 +/- 0.33 cm2. During swallowing, the UES moved in an orad direction. Localizing the UES sonographically, the peak UES pressure in the cadavers was 19.7 +/- 10.0 mm Hg. The UES has a greater muscular CSA and resting pressure than the upper esophageal body. In the cadaver studies, the UES was imaged in conjunction with a significant increase in pressure, indicating that the pressure is due to passive mechanical conformational changes.
Authors:
Larry S Miller; Qing Dai; Brett A Sweitzer; Vinod Thangada; Joseph K Kim; Beje Thomas; Henry Parkman; Ahmed M Soliman
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Digestive diseases and sciences     Volume:  49     ISSN:  0163-2116     ISO Abbreviation:  Dig. Dis. Sci.     Publication Date:  2004 May 
Date Detail:
Created Date:  2004-07-19     Completed Date:  2004-08-06     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7902782     Medline TA:  Dig Dis Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  703-9     Citation Subset:  AIM; IM    
Affiliation:
Temple University School of Medicine, Philadelphia, Pennsylvania, USA. vivi@astro.temple.edu
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MeSH Terms
Descriptor/Qualifier:
Adult
Deglutition / physiology
Endosonography / methods*
Esophagogastric Junction / anatomy & histology*,  physiology*,  ultrasonography
Female
Gastrointestinal Motility / physiology
Humans
Male
Manometry / methods*
Pressure
Rest / physiology
Grant Support
ID/Acronym/Agency:
R01 DK59500-03/DK/NIDDK NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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