| Evaluation of the upper esophageal sphincter (UES) using simultaneous high-resolution endoluminal sonography (HRES) and manometry. | |
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MedLine Citation:
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PMID: 15259487 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aim of this study was to characterize the motion, morphology, and pressure of the upper esophageal sphincter (UES). The UES and its surrounding structures were evaluated in seven normal subjects and four human cadavers, using simultaneous high-resolution endoluminal sonography and manometry. The UES musculature on ultrasound is a C-shaped structure with an angle of 107 +/- 19 degrees. The mean peak resting UES pressure was 74 mm Hg, with a total cross-sectional area (CSA) of 0.87 +/- 0.33 cm2. During swallowing, the UES moved in an orad direction. Localizing the UES sonographically, the peak UES pressure in the cadavers was 19.7 +/- 10.0 mm Hg. The UES has a greater muscular CSA and resting pressure than the upper esophageal body. In the cadaver studies, the UES was imaged in conjunction with a significant increase in pressure, indicating that the pressure is due to passive mechanical conformational changes. |
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Authors:
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Larry S Miller; Qing Dai; Brett A Sweitzer; Vinod Thangada; Joseph K Kim; Beje Thomas; Henry Parkman; Ahmed M Soliman |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Digestive diseases and sciences Volume: 49 ISSN: 0163-2116 ISO Abbreviation: Dig. Dis. Sci. Publication Date: 2004 May |
Date Detail:
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Created Date: 2004-07-19 Completed Date: 2004-08-06 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 7902782 Medline TA: Dig Dis Sci Country: United States |
Other Details:
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Languages: eng Pagination: 703-9 Citation Subset: AIM; IM |
Affiliation:
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Temple University School of Medicine, Philadelphia, Pennsylvania, USA. vivi@astro.temple.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Deglutition / physiology Endosonography / methods* Esophagogastric Junction / anatomy & histology*, physiology*, ultrasonography Female Gastrointestinal Motility / physiology Humans Male Manometry / methods* Pressure Rest / physiology |
| Grant Support | |
ID/Acronym/Agency:
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R01 DK59500-03/DK/NIDDK NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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