Document Detail


Evaluation of tumour markers in patients with burning mouth syndrome.
MedLine Citation:
PMID:  12907215     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Burning mouth syndrome (BMS) is an enigmatous condition both for the patient and the clinician, and is diagnosed on the basis of the patient's symptoms when they have on examination an apparently healthy looking oral mucosa. A variety of local and systemic factors are known to contribute to burning mouth syndrome. Some authors reported that underlying malignancy could be a possible cause for BMS. In 23 patients with burning mouth syndrome as well as in 20 age, sex, and race matched healthy controls levels of tumour markers-CEA, CA 19-9, AFP, and CYFRA 21-1-were determined from sera. Immunoradiometric assay (IRMA) for detection of ELSA-CEA, ELSA-CA 19-9, ELSA 2-AFP, ELSA-CYFRA 21-1 (CIS bio international, ORIS group, France) was used. Statistical analysis showed no significant differences in the level of tumour markers CEA, CA 19-9, AFP, CYFRA 21-1 in patients with burning mouth syndrome when compared to the healthy controls. We can conclude that evaluation of tumour markers in patients with burning mouth syndrome is not useful and in terms of cost-benefit this investigation should not be performed in patients with burning mouth syndrome.
Authors:
V Vucićević-Boras; L J Lukinac; A Cekić-Arambasin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Oral oncology     Volume:  39     ISSN:  1368-8375     ISO Abbreviation:  Oral Oncol.     Publication Date:  2003 Oct 
Date Detail:
Created Date:  2003-08-08     Completed Date:  2003-11-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9709118     Medline TA:  Oral Oncol     Country:  England    
Other Details:
Languages:  eng     Pagination:  742-4     Citation Subset:  IM    
Affiliation:
School of Dental Medicine, University of Zagreb, Gundulićeva 5, Zagreb, Croatia. vvboras@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Burning Mouth Syndrome / blood*,  etiology
Case-Control Studies
Female
Humans
Male
Middle Aged
Neoplasms / complications,  diagnosis
Tumor Markers, Biological / blood*
Chemical
Reg. No./Substance:
0/Tumor Markers, Biological

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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