Document Detail


Evaluation and treatment of endometriosis.
MedLine Citation:
PMID:  23317074     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Endometriosis, which affects up to 10 percent of reproductive-aged women, is the presence of endometrial tissue outside of the uterine cavity. It is more common in women with pelvic pain or infertility (25 to 40 percent and 70 to 90 percent, respectively). Some women with endometriosis are asymptomatic, whereas others present with symptoms such as debilitating pelvic pain, dysmenorrhea, dyspareunia, and decreased fertility. Diagnosis of endometriosis in primary care is predominantly clinical. Initial treatment includes common agents used for primary dysmenorrhea, such as nonsteroidal anti-inflammatory drugs, combination estrogen/progestin contraceptives, or progestin-only contraceptives. There is some evidence that these agents are helpful and have few adverse effects. Referral to a gynecologist is necessary if symptoms persist or the patient is unable to become pregnant. Laparoscopy is commonly used to confirm the diagnosis before additional treatments are pursued. Further treatments include gonadotropin-releasing hormone analogues, danazol, or surgical removal of ectopic endometrial tissue. These interventions may control symptoms more effectively than initial treatments, but they can have significant adverse effects and limits on duration of therapy.
Authors:
Sarina Schrager; Julianne Falleroni; Jennifer Edgoose
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American family physician     Volume:  87     ISSN:  1532-0650     ISO Abbreviation:  Am Fam Physician     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-01-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  1272646     Medline TA:  Am Fam Physician     Country:  United States    
Other Details:
Languages:  eng     Pagination:  107-13     Citation Subset:  AIM; IM    
Affiliation:
University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
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