| Evaluation of tissue oxygen measurements for flap monitoring in an animal model. | |
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MedLine Citation:
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PMID: 18677682 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Tissue oxygen tension (p(ti)O(2)) measurements are common in neurosurgery but uncommon in plastic surgery. We examined this technique as a monitoring method with probe placement in the subcutaneous tissue and addressed the importance of probe placement. Myocutaneous flaps were raised in an animal model and p(ti)O(2) measurements performed at different levels in the subcutaneous fat. Flap artery and vein were occluded until a 50% p(ti)O(2) reduction had occurred (T(1/2)). We found no significant effect of depth (P>0.10) on the level of p(ti)O(2). T(1/2)(arterial) was 7.2 minutes and T(1/2)(venous) was 18 minutes. We found no significant relation between initial levels of p(ti)O(2) and T(1/2). Location of the probe and absolute p(ti)O(2) value is of little relevance for flap monitoring. It is the relative change in p(ti)O(2) that is important. The p(ti)O(2) technique is well suited for monitoring in the subcutaneous tissue and is highly sensitive to changes in both arterial and venous blood flow. |
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Authors:
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Christian Bonde; Niels-Henrik Holstein-Rathlou; Jens Elberg |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2008-08-01 |
Journal Detail:
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Title: Journal of reconstructive microsurgery Volume: 24 ISSN: 0743-684X ISO Abbreviation: J Reconstr Microsurg Publication Date: 2008 Aug |
Date Detail:
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Created Date: 2008-08-26 Completed Date: 2009-01-06 Revised Date: 2011-02-16 |
Medline Journal Info:
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Nlm Unique ID: 8502670 Medline TA: J Reconstr Microsurg Country: United States |
Other Details:
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Languages: eng Pagination: 391-6 Citation Subset: IM |
Affiliation:
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Department of Plastic Surgery and Treatment of Burns, Copenhagen University Hospital, Copenhagen, Denmark. ctbonde@gmail.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Models, Animal Monitoring, Physiologic* Oxygen Oxygen Consumption* Subcutaneous Tissue / metabolism Surgical Flaps* / blood supply Sus scrofa |
| Chemical | |
Reg. No./Substance:
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7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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