Document Detail

Evaluation of temperature sensitivity of human papillomavirus type 11 by using the human xenograft severe combined immunodeficiency mouse model.
MedLine Citation:
PMID:  8077406     Owner:  NLM     Status:  MEDLINE    
The temperature sensitivity of human papillomavirus type 11 was evaluated by using a human xenograft severe combined immunodeficiency mouse model. Incubation of the virus for 1 h at a temperature higher than 56 degrees C but lower than 72 degrees C was sufficient to inhibit the virally induced growth of infected human tissue. However, 100 degrees C was necessary to completely inactivate HPV type 11 genome expression.
W Bonnez; R C Rose; C Borkhuis; C Da Rin; R C Reichman
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of clinical microbiology     Volume:  32     ISSN:  0095-1137     ISO Abbreviation:  J. Clin. Microbiol.     Publication Date:  1994 Jun 
Date Detail:
Created Date:  1994-10-06     Completed Date:  1994-10-06     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  7505564     Medline TA:  J Clin Microbiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1575-7     Citation Subset:  IM; X    
Department of Medicine, University of Rochester School of Medicine and Dentistry, New York 14642.
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MeSH Terms
Base Sequence
Condylomata Acuminata / virology*
DNA Probes, HPV
Mice, SCID*
Molecular Sequence Data
Papillomaviridae / classification,  physiology*
Penile Neoplasms / virology*
Severe Combined Immunodeficiency / virology
Skin / virology
Skin Transplantation
Subrenal Capsule Assay
Transplantation, Heterologous
Grant Support
Reg. No./Substance:
0/DNA Probes, HPV

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