| Evaluation of software for introducing protein structure: Visualization and simulation. | |
| | |
MedLine Citation:
|
PMID: 21567846 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Communicating an understanding of the forces and factors that determine a protein's structure is an important goal of many biology and biochemistry courses at a variety of levels. Many educators use computer software that allows visualization of these complex molecules for this purpose. Although visualization is in wide use and has been associated with student learning, it is quite challenging to develop visualizations that allow students to interactively observe the effects of altered amino acid sequence on protein structure. A software simulation, the protein investigator (PI), has been developed to specifically facilitate this type of exploration. When using the PI, students enter or edit an amino acid sequence; the software then simulates its folding in two dimensions using the major forces involved in protein structure. This study explores freshman undergraduate students' use of visualization and simulation when learning about protein structure. It also evaluates some of the learning outcomes from these two approaches. Our results show that simulation leads to similar learning outcomes as visualization. Because simulation allows a more interactive exploration, a combination of the two approaches may be an effective approach to introducing the basic principles of protein structure. |
| | |
Authors:
|
Brian White; Azmin Kahriman; Lois Luberice; Farhia Idleh |
Related Documents
:
|
7795716 - Neural network assisted cardiac auscultation. 16496436 - Classification of mental tasks from eeg signals using extreme learning machine. 7978246 - Sulfate detection in glycoprotein-derived oligosaccharides by artificial neural network... 17336546 - Persistence of improvements in postural strategies following motor control training in ... 21248026 - Students' personal traits, violence exposure, family factors, school dynamics and the p... 19410336 - Medical student core curriculum in dermatology survey. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology Volume: 38 ISSN: 1539-3429 ISO Abbreviation: Biochem Mol Biol Educ Publication Date: 2010 Sep |
Date Detail:
|
Created Date: 2011-05-13 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 100970605 Medline TA: Biochem Mol Biol Educ Country: United States |
Other Details:
|
Languages: eng Pagination: 284-9 Citation Subset: - |
Copyright Information:
|
Copyright © 2010 International Union of Biochemistry and Molecular Biology, Inc. |
Affiliation:
|
Department of Biology, University of Massachusetts, Boston, Massachusetts 02125. brian.white@umb.edu. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Cation transport coupled to ATP hydrolysis by the (Na, K)-ATPase: An integrated, animated model.
Next Document: Calibrated peer review for computer-assisted learning of biological research competencies.