|Evaluation of serological cross-reactivity between antibodies to Plasmodium and HTLV-III/LAV.|
|PMID: 2874279 Owner: NLM Status: MEDLINE|
|Serum samples from 460 patients with existing or previous Plasmodium infections, high antimalarial antibody titres, and no apparent risk of exposure to human T-lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) were assayed for HTLV-III/LAV antibody; only 1 sample, from a 21-year-old African woman, was strongly reactive by enzyme-linked immunosorbent assay (ELISA) and positive by western blot. Conversely, no sample from 100 HTLV-III/LAV-positive American homosexual men was strongly reactive for antibodies to the four Plasmodium species that infect human beings by an indirect fluorescent antibody technique, or for antibodies to Plasmodium falciparum by an ELISA technique. Thus, exposure to Plasmodium does not result in HTLV-III/LAV seropositivity, and HTLV-III/LAV antibodies are not strongly cross-reactive with malarial antigens.|
|A E Greenberg; C A Schable; A J Sulzer; W E Collins; Phuc Nguyen-Dinh|
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|Type: Journal Article|
|Title: Lancet Volume: 2 ISSN: 0140-6736 ISO Abbreviation: Lancet Publication Date: 1986 Aug|
|Created Date: 1986-09-17 Completed Date: 1986-09-17 Revised Date: 2004-11-17|
Medline Journal Info:
|Nlm Unique ID: 2985213R Medline TA: Lancet Country: ENGLAND|
|Languages: eng Pagination: 247-9 Citation Subset: AIM; IM; X|
|APA/MLA Format Download EndNote Download BibTex|
Acquired Immunodeficiency Syndrome
Antibodies / immunology*
Antibodies, Viral / immunology*
Enzyme-Linked Immunosorbent Assay
Fluorescent Antibody Technique
Malaria / immunology
Plasmodium / immunology*
|0/Antibodies; 0/Antibodies, Viral; 0/HIV Antibodies|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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