Document Detail


Evaluation of seafood toxicity in the Australes archipelago (French Polynesia) using the neuroblastoma cell-based assay.
MedLine Citation:
PMID:  23286347     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Ciguatera fish poisoning (CFP), a disease caused by consuming fish that have accumulated ciguatoxins (CTXs) in their tissue, is regarded as the most prevalent form of intoxication in French Polynesia. Recently, the Australes, one of the least affected archipelago until the early 1980s, has shown a dramatic increase in its incidence rates in 2009 with unusual CFP cases. In the present work, potential health hazards associated with the proliferation of various marine phytoplankton species and the consumption of fish and marine invertebrates highly popular among local population were assessed in three Australes islands: Raivavae, Rurutu and Rapa. Extracts from the marine dinoflagellates Gambierdiscus, Ostreospis and mat-forming cyanobacteria as well as fish, giant clams and sea urchin samples were examined for the presence of CTXs and palytoxin (PLTX) by using the neuroblastoma cell-based assay (CBA-N2a). Cytotoxic responses observed with both standards (Pacific CTX-3C and PLTX) and targeted marine products indicate that CBA-N2a is a robust screening tool, with high sensitivity and good repeatability and reproducibility. In Rurutu and Raivavae islands, our main findings concern the presence of CTX-like compounds in giant clams and sea urchins, suggesting a second bio-accumulation route for CFP toxins in the ciguatera food chain. In Rapa, the potential CFP risk from Gambierdiscus bloom and fish was confirmed for the first time, with levels of CTXs found above the consumer advisory level of 0.01 ng Pacific CTX-1B g(-1) of flesh in three fish samples. However, despite the presence of trace level of PLTX in Ostreopsis natural assemblages of Rapa, no sign of PLTX accumulation is yet observed in tested fish samples. Because this multi-toxinic context is likely to emerge in most French Polynesian islands, CBA-N2a shows great potential for future applications in the algal- and toxin-based field monitoring programmes currently on hand locally.
Authors:
Ralph Pawlowiez; Hélène Taiana Darius; Philippe Cruchet; Fanny Rossi; Amandine Caillaud; Dominique Laurent; Mireille Chinain
Related Documents :
8813527 - Isatin inhibits food intake in mice.
605167 - Some effects of a split litter cross foster design applied to 15 day old rat pups.
6016237 - Lateral hypothalamus: hoarding behavior elicited by electrical stimulation.
16866597 - Affect regulation and food intake in bulimia nervosa: emotional responding to food cues...
9501377 - The role of seafood in foodborne diseases in the united states of america.
12914427 - Reproductive patterns and feeding habits of three nectarivorous bats (phyllostomidae: g...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-4
Journal Detail:
Title:  Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment     Volume:  -     ISSN:  1944-0057     ISO Abbreviation:  Food Addit Contam Part A Chem Anal Control Expo Risk Assess     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101485040     Medline TA:  Food Addit Contam Part A Chem Anal Control Expo Risk Assess     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
a Ecosystèmes Insulaires Océaniens, UMR241, Laboratoire des Microalgues Toxiques , Institut Louis Malardé , BP30 Papeete , 98713, French Polynesia.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Premating isolation is determined by larval rearing substrates in cactophilic Drosophila mojavensis....
Next Document:  Synthesis, Structures, and Photochemistry of Tricarbonyl Metal Polyoxoanion Complexes, [X(2)W(20)O(7...