Document Detail

Evaluation of the safety and efficacy of topical nitroglycerin ointment to facilitate venous cannulation.
MedLine Citation:
PMID:  8047423     Owner:  NLM     Status:  MEDLINE    
The purpose of this study was to determine the safety and efficacy of 2% nitroglycerin ointment to facilitate venous cannulation. In a double-blind experimental design, 80 adult subjects were randomly assigned to receive a 2% nitroglycerin ointment or a placebo ointment prior to cannulation. Variables measured before and after ointment application included heart rate, electrocardiogram, vein size, and presence of headache. No statistically significant differences were found in vein size or adverse effects following nitroglycerin ointment application.
P Griffith; B James; A Cropp
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Nursing research     Volume:  43     ISSN:  0029-6562     ISO Abbreviation:  Nurs Res     Publication Date:    1994 Jul-Aug
Date Detail:
Created Date:  1994-08-30     Completed Date:  1994-08-30     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0376404     Medline TA:  Nurs Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  203-6     Citation Subset:  AIM; IM; N    
Critical Care/Heart, Lung and Blood Nursing Service, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, MD.
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MeSH Terms
Administration, Topical
Bloodletting / instrumentation,  methods*
Headache / chemically induced
Hemodynamics / drug effects
Middle Aged
Nitroglycerin / administration & dosage*,  adverse effects,  blood
Time Factors
Reg. No./Substance:
0/Ointments; 55-63-0/Nitroglycerin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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