| Evaluation of the response to pharmacological stress in chronic aortic regurgitation. | |
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MedLine Citation:
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PMID: 11567594 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We evaluated the hemodynamic response of patients with chronic aortic regurgitation and decreased ejection fraction (EF), mean value +/- SD (37 +/- 9), to dobutamine stress echocardiography (DSE). Eleven patients were studied with DSE. Nine patients were in New York Heart Association (NYHA) Class II and two in NYHA Class III. Ten patients received medical treatment in the only other periodic evaluation. With DSE in nine patients, a significant decrease in left ventricular end-diastolic and end-systolic diameters (LVEDD and LVESD) as well as LV end-diastolic and end-systolic volumes (LVEDV and LVESV) was documented in comparison to resting values. EF and fractional shortening (FS) improved significantly with DSE. Systolic wall stress (SWS) and pulmonary arterial systolic pressure (PASP) did not change. Average follow-up was 6.7 months. Three patients underwent valve replacement with mechanical prostheses. Two of them are in NYHA Class I and the other died of LV failure 3 days after surgery. One patient deteriorated beyond surgical treatment and was in NYHA Class II. The other seven patients remain in NYHA Class II and await valve replacement. In patients with chronic aortic regurgitation and depressed EF, the variables relevant to myocardial reserve appear to be EF, FS, LVEDD, LVESD, LVEDV, and LVESV. |
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Authors:
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N Espinola-Zavaleta; N Gómez-Núñez; P Y Chávez; G Sahagun-Sánchez; C Keirns; J M Casanova; A Romero-Cárdenas; F J Roldán; J Vargas-Barrón |
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Publication Detail:
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Type: Comparative Study; Evaluation Studies; Journal Article |
Journal Detail:
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Title: Echocardiography (Mount Kisco, N.Y.) Volume: 18 ISSN: 0742-2822 ISO Abbreviation: Echocardiography Publication Date: 2001 Aug |
Date Detail:
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Created Date: 2001-09-24 Completed Date: 2001-12-04 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8511187 Medline TA: Echocardiography Country: United States |
Other Details:
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Languages: eng Pagination: 491-6 Citation Subset: IM |
Affiliation:
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Department of Echocardiography, Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano No. 1, Colonia Sección XVI, Tlalpan, México, D.F., Mexico. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aortic Valve Insufficiency / diagnosis*, ultrasonography Chronic Disease Dobutamine / diagnostic use* Echocardiography / methods Exercise Test* Female Follow-Up Studies Humans Male Middle Aged Stroke Volume / drug effects, physiology Ventricular Function, Left / drug effects, physiology |
| Chemical | |
Reg. No./Substance:
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34368-04-2/Dobutamine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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