Document Detail


Evaluation of the relative efficacy of copolymerized polylactic-polyglycolic acids alone and in conjunction with polyglactin 910 membrane in the treatment of human periodontal infrabony defects: A clinical and radiological study.
MedLine Citation:
PMID:  21525683     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Background: Absorbable synthetic biopolymers have been used as bone filler in Periodontology, proving effective stimulants to bone regeneration. Aim: Copolymerized polylactic and polyglycolic acid is used as a bone filler and polyglactin 910 as a guided tissue regeneration (GTR) membrane to achieve regeneration in periodontal infrabony defects. Materials and Methods: Forty patients with two- or three-walled infrabony defects were selected and randomly divided into two groups. Group A included patients treated with polylactic-polyglycolic acids 50:50 (Fisiograft® ,Ghimsa SPA,Via Fucini, Italy) alone and Group B included patients treated with polylactic-polyglycolic acids (PLA-PGA)50:50 in conjunction with polyglactin acid 910 (Vicryl Mesh® Johnson&Johnson , U.S.A ). Evaluation of clinical parameters probing depth and attachment level and radiographs was done preoperatively and 12 and 24 weeks postoperatively. Results: Both the groups showed statistically significant mean reduction in probing depth and gain in clinical attachment level and linear bone fill. Conclusions: Within the limit of this study, both the treatment modalities are beneficial for the treatment of infrabony defects.
Authors:
Vipin Chhabra; Amarjit Singh Gill; Poonam Sikri; Nandini Bhaskar
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Indian journal of dental research : official publication of Indian Society for Dental Research     Volume:  22     ISSN:  1998-3603     ISO Abbreviation:  Indian J Dent Res     Publication Date:    2011 Jan-Feb
Date Detail:
Created Date:  2011-04-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9202990     Medline TA:  Indian J Dent Res     Country:  India    
Other Details:
Languages:  eng     Pagination:  83-9     Citation Subset:  D    
Affiliation:
Department of Periodontics and Implantology, BRS Dental College and Hospital, Barwala, Panchkula, India.
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