Document Detail


Evaluation of the regional ventricular systolic function by two-dimensional strain echocardiography in gestational diabetes mellitus (GDM) fetuses with good glycemic control.
MedLine Citation:
PMID:  25367553     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Abstract Objective: The aim is to quantitatively assess regional ventricular systolic function by two-dimensional strain (2DS) echocardiography in gestational diabetes mellitus (GDM) fetuses with good glycemic control. Methods: We studied 60 consecutive normal fetuses and 35 fetuses of GDM mothers with good glycemic control by echocardiography. M-mode and two-dimensional echocardiography were used to measure ejection fraction (EF) and wall dimensions of left ventricle and right ventricle. Both left and right ventricle peak systolic myocardial strain values were obtained by 2DS echocardiography. Results: Compared with normal fetuses, the thickness of the interventricular septum and the thickness of right ventricular wall were significantly increased in GDM fetuses p<0.05). Compared with those of normal fetuses, the peak systolic myocardial strain decreased significantly in the apical segments of the interventricular septum and the apical segments of the left ventricular lateral wall in GDM fetuses (p<0.05), as well as the apical and middle segments of right ventricular wall in GDM fetuses (p<0.05). Peak negative 2D-S values in 60 normal fetuses increased with the gestational age, showing a significant linear correlation(r=-0.625, p<0.001). The average ventricular strain was not correlated to ventricular wall thickness (r=0.127, p=0.394). Conclusions: 2DS is a feasible approach to assess regional ventricular systolic function in the fetal hearts and it can be used to examine cardiac systolic function in GDM fs with good glycemic control.
Authors:
Hongying Wang; Yi Xu; Jing Fu; Lan Huang
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-11-4
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  -     ISSN:  1476-4954     ISO Abbreviation:  J. Matern. Fetal. Neonatal. Med.     Publication Date:  2014 Nov 
Date Detail:
Created Date:  2014-11-4     Completed Date:  -     Revised Date:  2014-11-5    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1-16     Citation Subset:  -    
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