Document Detail


Evaluation of a rapid method for preparation of fatty acid methyl esters for analysis by gas-liquid chromatography.
MedLine Citation:
PMID:  4044736     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The major limitation to fatty acid analysis by gas-liquid chromatography is associated with preparation of fatty acid methyl esters (FAME). In the present study, FAME preparations were made from plant oils (corn, olive, sunflower), sunflower oil margarine, lard and various animal tissue fats by a rapid transesterification involving tetramethylammonium hydroxide in methanol, and also by a longer conventional saponification-esterification method. Fats from animal (beef, mutton, pork) adipose tissues were extracted by a simpler modified procedure and also by the Folch method prior to the rapid and the conventional FAME preparations, respectively. FAME analysis on a gas-liquid chromatograph equipped with a Silar 10C glass capillary column indicated similar fatty acid composition of a given fat or oil, whether FAME was prepared by the rapid or the longer conventional method. The data obtained by both methods were very highly correlated for all the fats (r = 0.9895 - 0.9999). However, the rapid method showed a tendency for enhanced recoveries of lower chain fatty acids (e.g. 14:0), and also of unsaturated C18 isomers. Possibly, losses of fatty acids that occurred during the lengthy fat extraction, fatty acid esterification or ether-evaporation FAME concentration steps (conventional method) were minimised by the single transesterification step (rapid method). This rapid transesterification method appears to be an attractive alternative to FAME preparation from a wide variety of different fats for gas-liquid chromatographic analysis.
Authors:
R Misir; B Laarveld; R Blair
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of chromatography     Volume:  331     ISSN:  0021-9673     ISO Abbreviation:  J. Chromatogr.     Publication Date:  1985 Aug 
Date Detail:
Created Date:  1985-11-13     Completed Date:  1985-11-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0427043     Medline TA:  J Chromatogr     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  141-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Carboxylic Acids / chemical synthesis*
Cattle
Chromatography, Gas
Dietary Fats / analysis*
Esters / analysis,  chemical synthesis*
Fatty Acids / analysis,  isolation & purification
Margarine / analysis
Oils / analysis
Sheep
Swine
Chemical
Reg. No./Substance:
0/Carboxylic Acids; 0/Dietary Fats; 0/Esters; 0/Fatty Acids; 0/Oils; 8029-82-1/Margarine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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