Document Detail

Evaluation of radioprotective effect of aloe vera and zinc/copper compounds against salivary dysfunction in irradiated rats.
MedLine Citation:
PMID:  25231144     Owner:  NLM     Status:  In-Data-Review    
The aim of this study was to evaluate the radioprotective and reparative effects of compounds based on aloe vera, zinc, and copper against salivary gland dysfunction in Wistar rats. A total of 150 Wistar rats were randomly divided into 12 groups, in which the animals received aloe vera and/or zinc and copper. In eight of these groups the animals were also subjected to irradiation before or after administration of the substances. After 27 days, sialometry tests were performed. Data were analyzed using ANOVA and the Tukey test (P < 0.05). Rats that had been administered aloe vera before or after irradiation showed a significantly higher salivary flow rate than rats that had been simply irradiated. When both substances were administered, a statistically significant difference in the salivary flow rate was observed in comparison with the irradiation alone group seven days after irradiation. The present results suggest that aloe vera exerts positive protective and reparative effects, and can be considered a potential radioprotective substance. (J Oral Sci 56, 191-194, 2014).
Yuri Nejaim; Amaro I V Silva; Taruska V Vasconcelos; Emmanuel J N L Silva; Solange M de Almeida
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of oral science     Volume:  56     ISSN:  1880-4926     ISO Abbreviation:  J Oral Sci     Publication Date:  2014  
Date Detail:
Created Date:  2014-09-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9808942     Medline TA:  J Oral Sci     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  191-4     Citation Subset:  D; IM    
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