| Evaluation of radioimmunoassays: comparison of dose interpolation calculations by four parameter logistic and spline functions. | |
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MedLine Citation:
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PMID: 3546584 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Two computerized methods for dose interpolation calculation were compared. Generated data sets with a known coefficient of variation as well as laboratory RIA data were analysed. The four parameter logistic method, which is based on an approximation of the mass action law, performed better than the Spline method, a procedure which makes no a priori assumptions about the data. Correct weighting of the data was important for obtaining satisfactory fits. The determination of the response error relationship proved to be the most satisfactory approach in obtaining suitable weighting factors. |
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Authors:
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M Kraupp; R März; E Legenstein; B Knerer; T Szekeres |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of clinical chemistry and clinical biochemistry. Zeitschrift für klinische Chemie und klinische Biochemie Volume: 24 ISSN: 0340-076X ISO Abbreviation: J. Clin. Chem. Clin. Biochem. Publication Date: 1986 Dec |
Date Detail:
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Created Date: 1987-03-30 Completed Date: 1987-03-30 Revised Date: 2007-07-24 |
Medline Journal Info:
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Nlm Unique ID: 7701860 Medline TA: J Clin Chem Clin Biochem Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 1023-8 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Biopterin
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analogs & derivatives,
blood Dose-Response Relationship, Drug Humans Insulin / blood Mathematical Computing* Monte Carlo Method Neopterin Numerical Analysis, Computer-Assisted* Quality Control Radioimmunoassay* |
| Chemical | |
Reg. No./Substance:
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11061-68-0/Insulin; 22150-76-1/Biopterin; 670-65-5/Neopterin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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