Document Detail

Evaluation of pulmonary vein stenosis after catheter ablation of atrial fibrillation.
MedLine Citation:
PMID:  12438819     Owner:  NLM     Status:  MEDLINE    
Pulmonary vein (PV) stenosis has emerged recently as an important issue in patients who received radiofrequency (RF) ablation of atrial fibrillation (AF). Serial pathophysiological responses, including thrombosis, metaplasia, proliferation and neovascularization, may lead to PV stenosis after RF energy application around or inside the PV ostia. The clinical manifestations of PV stenosis consist of chest pain, dyspnea, cough, hemoptysis, recurrent lung infection and pulmonary hypertension. Although PV stenosis can be asymptomatic, its severity may be related to the numbers of stenotic PVs, the degree and chronicity of PV stenosis. The incidence of PV stenosis (defined as luminal diameter reduction >50%) detected by spiral computer tomography scan or three dimensional magnetic resonance angiography was from 0 to 7% per PV after isolation of PVs from left atria. Furthermore, some patients may show late progression of PV stenosis during follow-up. The first choice of treatment for symptomatic PV stenosis is PV angioplasty with stenting; however, restenosis were reported occasionally. Several studies have analyzed the predictors of PV stenosis, and the results are controversial. However, the consensus for prevention of PV stenosis should include less energy application and the ablation site more close to the atrial site.
Hsuan-Ming Tsao; Shih-Ann Chen
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Publication Detail:
Type:  Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Cardiac electrophysiology review     Volume:  6     ISSN:  1385-2264     ISO Abbreviation:  Card Electrophysiol Rev     Publication Date:  2002 Dec 
Date Detail:
Created Date:  2002-11-19     Completed Date:  2003-05-15     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9708907     Medline TA:  Card Electrophysiol Rev     Country:  United States    
Other Details:
Languages:  eng     Pagination:  397-400     Citation Subset:  IM    
Division of Cardiology, Department of Medicine, National Yang-Ming University, School of Medicine, Taipei, Taiwan.
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MeSH Terms
Angioplasty / instrumentation*,  methods
Atrial Fibrillation / diagnosis,  surgery*
Catheter Ablation / adverse effects*,  methods
Clinical Trials as Topic
Follow-Up Studies
Magnetic Resonance Angiography
Postoperative Complications / diagnosis
Primary Prevention / methods
Pulmonary Veno-Occlusive Disease / etiology*,  radiography,  surgery*
Risk Assessment
Severity of Illness Index
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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