Document Detail


Evaluation of predictors of clinical outcome after partial left ventriculectomy.
MedLine Citation:
PMID:  11465238     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Outcome after partial left ventriculectomy (PLV) is difficult to predict. Our goal was to determine if clinical measurements including exercise testing could predict outcome after PLV. METHODS: Sixteen patients with dilated cardiomyopathy had left ventricular ejection fraction, left ventricular end-diastolic diameter, amount of mitral regurgitation (MR), New York Heart Association (NYHA) functional class, and cardiopulmonary exercise testing measurements measured before PLV and 3 months after PLV. Eleven patients who remained stable after PLV (group 1) were compared with 5 patients who deteriorated after PLV (group 2). RESULTS: Similar significant improvements were seen in both groups 3 months post-PLV with respect to left ventricular ejection fraction (group 1: 0.136+/-0.037 to 0.212+/-0.046; group 2: 0.139+/-0.042 to 0.179+/-0.073) and left ventricular end-diastolic diameter (group 1: 8.5+/-0.7 to 7.0+/-0.6 cm; group 2: 7.6+/-0.6 to 6.5+/-0.6 cm). The MR grade (1.0+/-0.6 versus 2.5+/-0.6), NYHA functional class (1.5+/-0.31 versus 2.5+/-0.6), and peak oxygen consumption (17.8+/-1.1 versus 12.2+/-2.0) were significantly different in the two groups 3 months after PLV (p < 0.05, analysis of variance). CONCLUSIONS: Patients that do not show significant improvement in peak oxygen consumption, NYHA class and significant decrease in the amount of MR 3 months after PLV, compared with pre-PLV, are at increased risk of clinically deteriorating.
Authors:
G Bhat; R D Dowling
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Publication Detail:
Type:  Evaluation Studies; Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  72     ISSN:  0003-4975     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  2001 Jul 
Date Detail:
Created Date:  2001-07-23     Completed Date:  2001-08-09     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  91-5     Citation Subset:  AIM; IM    
Affiliation:
Department of Medicine, University of Louisville, Kentucky, USA. g0bhat01@gwise.louisville.edu
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Cardiomyopathy, Dilated / mortality,  physiopathology,  surgery*
Exercise Test
Female
Heart Failure / mortality,  physiopathology,  surgery*
Heart Ventricles / surgery
Hemodynamics / physiology
Hospital Mortality
Humans
Male
Middle Aged
Oxygen Consumption / physiology
Postoperative Complications / mortality,  physiopathology
Prognosis
Stroke Volume / physiology
Survival Rate
Ventricular Dysfunction, Left / mortality,  physiopathology,  surgery*
Ventricular Function, Left / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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