Document Detail

Evaluation of postresuscitation left ventricular global and segmental function by radionuclide ventriculography in sudden coronary death survivors of prehospital cardiac arrest: Correlation to subsequent short-term prognosis.
MedLine Citation:
PMID:  7055045     Owner:  NLM     Status:  MEDLINE    
Previous data have shown that patients with significant left ventricular (LV) dysfunction, marked abnormalities in resting hemodynamics, and multiple vessel coronary artery disease (CAD) are at increased risk for sudden cardiac death. However, in-hospital assessment of ventricular function in the early postresuscitation period of out-of-hospital cardiac arrest has not been evaluated and related to short-term outcome. By using bedside radionuclide ventriculography (RNV) we evaluated LV ejection fraction (LVEF) and wall motion in 36 nonconsecutive patients within 24 hours of their episode of out-of-hospital cardiac arrest. There were 24 men and 12 women with mean age of 62.3 years (range 21 to 85 years). Total mortality of the entire group was 38.8% at 4 weeks. Eighteen patients had LVEF less than 0.30 and 18 had LVEF greater than 0.30. Mortality in the low LVEF group was 55.5% at 4 weeks versus 22.2% in patients with LVEF greater than 0.30 (p less than 0.05). Patients with normal LV wall motion had no short-term mortality (none of seven), while patients having abnormal LV wall motion had a significantly higher short-term mortality (14 of 29) (p less than 0.05). We conclude that out-of-hospital cardiac arrest survivors have a high incidence of severe LV dysfunction in the early postresuscitation period and that a significantly higher early mortality is seen in the group with LVEF less than 0.30. In addition, abnormalities of LV wall motion by RNV examination demonstrated poorer prognosis in the first 4 weeks than patients with normal LV wall motion.
M J Ptacin; D D Tresch; J S Soin; H L Brooks
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American heart journal     Volume:  103     ISSN:  0002-8703     ISO Abbreviation:  Am. Heart J.     Publication Date:  1982 Jan 
Date Detail:
Created Date:  1982-03-22     Completed Date:  1982-03-22     Revised Date:  2006-02-27    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  54-6     Citation Subset:  AIM; IM    
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MeSH Terms
Coronary Disease / physiopathology
Death, Sudden* / etiology
Heart Arrest / physiopathology,  radionuclide imaging*
Heart Ventricles / physiopathology,  radionuclide imaging*
Middle Aged
Myocardial Infarction / complications

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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