Document Detail


Evaluation of polymer-coated balloon-expandable stents in bile ducts.
MedLine Citation:
PMID:  2916065     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The long-term patency of and biologic response to the presence of polymer-coated balloon-expandable intraluminal stents in the bile ducts was studied in 18 dogs. Metallic stents coated with two different polymers (silicone rubber and segmented polyether-polyurethane) were placed in 12 dogs and uncoated stents in six, and animals were killed after 4, 12, and 24 weeks of observation. Cholangiograms were obtained at 1, 4, 6, 12, and 24 weeks, depending on length of follow-up. All bile duct segments containing stents remained patent throughout the follow-up periods. Characteristic luminal narrowings due to hyperplastic papillary mucosa occurred with all three stent types. although no difference could be found in the degree of narrowing of the most restrictive segment among the three stent types, mucosal proliferation was most extensive with the uncoated stent. Lack of concretion buildup and benign tissue response encourage the development of a clinically useful expandable biliary endoprosthesis.
Authors:
R Alvarado; J C Palmaz; O J Garcia; F O Tio; C R Rees
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Radiology     Volume:  170     ISSN:  0033-8419     ISO Abbreviation:  Radiology     Publication Date:  1989 Mar 
Date Detail:
Created Date:  1989-03-23     Completed Date:  1989-03-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  975-8     Citation Subset:  AIM; IM    
Affiliation:
Department of Radiology, University of Texas Health Science Center, San Antonio 78284.
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MeSH Terms
Descriptor/Qualifier:
Animals
Balloon Dilatation / instrumentation*
Bile Ducts / pathology*
Biocompatible Materials*
Cholangiography
Dogs
Polyurethanes*
Prostheses and Implants*
Prosthesis Design
Silicone Elastomers*
Chemical
Reg. No./Substance:
0/Biocompatible Materials; 0/Polyurethanes; 0/Silicone Elastomers

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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