Document Detail

Evaluation of the persistence of the effect of ivermectin and abamectin against gastrointestinal and pulmonary nematodes in cattle.
MedLine Citation:
PMID:  9090034     Owner:  NLM     Status:  MEDLINE    
The persistence of the effect of ivermectin and abamectin against gastrointestinal nematodes and lungworm in cattle was evaluated in two trials, each involving 28 animals. Groups of seven cattle either remained untreated, or were treated topically with ivermectin at 500 micrograms/kg bodyweight or subcutaneously with either ivermectin or abamectin at 200 micrograms/kg bodyweight. Starting on the day of treatment the cattle were given daily trickle infections with various infective nematode larvae for two weeks (Haemonchus species, Trichostrongylus axei and Cooperia species), three weeks (Ostertagia ostertagi and Oesophagostomum radiatum) and four weeks (Dictyocaulus viviparus). The cattle were killed 49 to 51 days after treatment and their worm burdens measured. An efficacy of > 99 per cent was recorded in all the groups demonstrating that the products controlled Haemonchus species, T axei, C oncophora, C punctata and C surnabada for at least two weeks, O ostertagi and O radiatum for at least three weeks and D viviparus for at least four weeks.
D Barth; G F Ericsson; B N Kunkle; S Rehbein; W G Ryan; D H Wallace
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The Veterinary record     Volume:  140     ISSN:  0042-4900     ISO Abbreviation:  Vet. Rec.     Publication Date:  1997 Mar 
Date Detail:
Created Date:  1997-06-11     Completed Date:  1997-06-11     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0031164     Medline TA:  Vet Rec     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  278-9     Citation Subset:  IM    
Merck Research Laboratories, Rohrdorf, Germany.
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MeSH Terms
Administration, Topical
Anthelmintics / therapeutic use*
Antinematodal Agents / therapeutic use*
Cattle Diseases / drug therapy*,  parasitology
Gastrointestinal Diseases / drug therapy,  parasitology,  veterinary*
Injections, Intravenous
Ivermectin / analogs & derivatives*,  therapeutic use*
Lung Diseases / drug therapy,  parasitology,  veterinary*
Nematode Infections / drug therapy,  veterinary*
Reg. No./Substance:
0/Anthelmintics; 0/Antinematodal Agents; 70288-86-7/Ivermectin; 71751-41-2/abamectin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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